Capstar is the best oral flea treatment for cats whose active ingredient is the Nitenpyram. For dosage and administration of combined ingredient products, refer to information on the specific product. Fast Action and Effective - Fleas killed within 24 hours of application on cats - For tick control on cats, use FRONTLINE SPRAY. Methoprene-membrane interaction and perturbation of cell bioenergetics may underlie the mechanism of toxicity of this compound in non-target organisms. Combined ingredient products are supplied as topical solutions. This prevents the insects from reproducing. Methoprene is a hormone that comes in two forms: r-methoprene and s-methoprene. Avoid contact with eyes and skin. What is S-Methoprene? Poisoning by (S)-methoprene alone is rare due to its low toxicity. This application rate is ten times the suggested rates. By acting like an insect hormone, it interferes with insect growth and development. Frontline Plus has a rapid onset of action and kills re-infestations with newly acquired adult fleas for at least 1 month, and also prevents the development of flea eggs, larvae and pupae produced by any adult fleas acquired for up to 3 months after treatment. This page may not include all side effects, uses, brand names or applications. Includes three easy to use monthly applications. Generic Frontline Plus is safe for use in dogs and puppies, cats and kittens over 8 weeks of age and in breeding, pregnant or lactating bitches/queens. Smith C A (1995) Searching for safe methods of flea control. Frontline Plus is made of two major ingredients – fipronil and (S)-methoprene. Boehringer Ingelheim Animal Health Australia Pty Ltd, Waterfast or Water Resistant for a month after 48 hours of application. Topical treatment that quickly and effectively kills fleas, flea eggs, deer ticks, and repels mosquitos. The Animal Pharmacy is an Australian supplier of prescription and non-prescription veterinary medicines. For external use only. The Best Essential Oils for Cats Cedarwood . Fipronil, methoprene, and etofenprox is a combination flea and tick control product that kills existing fleas and ticks to eliminate and prevent infestations for one month following application. This compound mimics the action of juvenile hormone and causes impaired development and death of the developing stages of fleas. Methoprene is commonly found in flea treatments for dogs and cats, in cattle feed to control flies, and in mosquito control products. LD50 acute, rats, p.o. In addition, the insect growth inhibitor s-methoprene kills flea eggs and larvae and thus disrupts the life cycle of ticks and fleas. Methoprene is a compound that mimics the action of an insect growth regulation hormone. Methoprene is the common name for isopropyl-(2E,4E,7R,S)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate.It is a racemic mixture of two enantiomers (R and S in a ratio of 1:1). If product enters eyes, wash it out immediately with water. The veterinary medicinal product is exclusively indicated when all three groups are targeted at the same time.EctoparasitesTreatment and prevention of infestations by fleas (Ctenocephalides felis). Treatment and prevention of flea infestations and biting lice and control of flea allergy dermatitis on cats. Formulated for cats and kittens over 5 pounds that are 12 weeks of age or older. The Animal Pharmacy has the largest range and the cheapest prescription animal medicines in Australia. It has also been used to treat Cheyletiellosis(Walking Dandruff Mite)in dogs and cats. For the best experience on our site, be sure to turn on Javascript in your browser. Safe to use on kittens from 8 weeks of age or older. caterpillar) to the adult phase (i.e. An insect growth regulator, (S)-methoprene [90 g/L (9%) for dogs or 120 g/L (12%) for cats], has also been included with several of the products containing fipronil (e.g. Rapid and long-acting treatment and prevention of flea infestations on cats and persistent effect on environmental stages of fleas. Pet Bucket Ltd is a UK registered company | Company no: 08345021 | BTC Bessemer Drive Stevenage | SG1 2DX UK, Duoflect Topical Solution for Dogs and Cats (with Fipronil). All Rights Reserved. Administration to kittens under 8 weeks of age; administration to rabbits. Frontline Plus for dogs or cats and Startgard Plus for puppies or kittens). LD50 acute, rats, dermal, >2000 mg/kg LD50 acute, dogs, dermal, >5000 mg/kg Etofenprox is less irritant than most pyrethroid esters (e.g. It works rapidly and is for use on dogs 12 weeks of age and older. For cats treated by topical application, the average eprinomectin (B1 a component) maximum plasma concentration (Cmax) was 20 ng/mL. Use fire-extinguishing media suitable for the surrounding fire. Prevents the development of flea eggs, larvae and pupae produced by adult fleas acquired for six weeks after treatment. Call us now for more info about our products on 02 8599 9759. Not available as a single ingredient product for use with household pets. The product is also beneficial in the control of chewing lice, mosquitoes, and mites. Fipronil and methoprene is used in the control and treatment of all stages of flea infestations and tick infestations in dogs and cats. Methoprene Cats. Fipronil aids in the control of sarcoptic mange infestations in dogs. Long Lasting - Kills and controls fleas for up to a month. Methoprene applied at a concentration of 0.2 ppm did not significantly affect the locomotor activities of mosquitofish or goldfish. The idea behind IGR use is that if a given insect cannot reach adulthood, it cannot reproduce. (S)-methoprene Dogs (≥ 9 wks; ≥ 5 lb) Donotuseoncats • Kills fleas (all life stages) • Repelsandkillsticks • Kills chewing lice EasySpot (Novartis) Fipronil Cats (≥ 8 wks) • Kills fleas • Kills ticks and chewing lice Frontline Plus (Merial) Fipronil (S)-methoprene Dogs (≥ 8 wks) Cats (≥ 8 wks) Side effects experienced by dogs and cats after treatment with products containing (S)-methoprene can generally be attributed to the other active or inert ingredients. In terms of region, the methoprene market can be categorized into North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. S-methoprene is a growth regulator that acts as an important juvenile hormone in insects to prevent pupa and larva from developing into adults. The maximum concentrations were reached 24 h after dosing in the majority of the animals (six of eight cats). Is cedarwood safe for cats? Will irritate the eyes and skin. s-Methoprene TG Extinguishing media Suitable extinguishing media The product is not flammable. It works by not allowing the target insect from reaching the point of maturity, which will halt the potential that it can reproduce. It is also used for the treatment and control of chewing lice in dogs, puppies, kittens and cats. Therefore methoprene is like “birth control” for pests. Unless you are a vet or have studied chemistry, it is unlikely that the name S-Methoprene means much to you. However, if you are a dog or cat owner, you might be interested to learn that S-Methoprene is in fact one of the active ingredients in the popular flea and tick control pet medications Frontline Plus for dogs and Frontline Plus for cats. (S)-methoprene alone is well tolerated by dogs and cats, with a low toxicity and high safety margin. The sesame oil helps the product to spread over the cat’s skin and acts as a coat conditioner as well. Effective formula stops the flea life cycle and prevents re-infestation for up to 30 days. As such (S)-methoprene is not used as a single ingredient product, but combined with adulticides such as Fipronil to extend the efficacy of flea treatments. It can be used on kittens from 8 weeks of age and is safe to use on breeding, pregnant or lactating animals. Frontline Plus for Cats . Methoprene is an insect growth regulator. According to the EPA, the chemical methoprene is considered an insect growth regulator. The average terminal half-life was 114 h due to slow absorption (‘flip-flop’ kinetics). (S)-methoprene is an insect growth regulator (IGR) of the class of compounds known as juvenile hormone analogues that inhibit the development of immature stages of insects. It is also used in insect baits and home insect sprays. It does not kill fleas but disrupts their life cycle, preventing early stages from developing into adults. However, if you suspect your pet has had an overdose of any medication, please contact your veterinarian immediately. Unsuitable extinguishing media Do not use water jet as an extinguisher, as this will spread the fire. Our pharmacy registration means that we can send medicines to all States and Territories of Australia. Absolutely! Our Mission is to help make treating your pet's diseases easier and more affordable. This chemical is extremely effective when used for several different types of insects and pests, which include: >2000 mg/kg. Frontline Plus (fipronil Plus (s)-methoprene) For Cats - Parasiticides - Cat - Breeding | Cat - Female (queen) | Cat - Over 8 Weeks Of Age | Castrate | Cat - Queen - Catbiting Louse | Flea - Ctenocephalides Spp. | Flea Allergic Dermatitis | Cat Louse - Poison Schedule: Explanation. Uses of Fipronil and Methoprene for Dogs and Cats Fipronil and methoprene is used in the control and treatment of all stages of flea infestations and tick infestations in dogs and cats. It is used as an insecticide because it interferes with the normal maturation process. Find the medicine listed in our inventory and follow the checkout process. Usually, the onset of action is 30 minutes, and its effect lasts for 48 hours upon which most adult fleas would have died. Long Lasting - Kills and controls fleas for up to a month, Safe to use on kittens from 8 weeks of age or older, Safe to use on lactating and pregnant cats. In addition, the oil must come from an Eastern Red Cedar (Juniperus virginiana), as the cedar oil from White cedar (Melia azedarach) is toxic to cats. To order a prescription medicine, make sure to follow these simple three steps. JAVMA 206(8) 1137-1143. Socha R et al (1990) Comments on safety of methoprene. Fipronil, methoprene, and cyphenothrin, when used properly, can significantly reduce the risk of numerous potentially serious diseases and conditions, including Lyme di… For cats with, or at risk from mixed infestations by cestodes, nematodes and ectoparasites. It can prevent normal molting, egg-laying, egg-hatching, and development from the immature phase (i.e. As such (S)-methoprene is not used as a single ingredient product, but combined with adulticides … For the best experience on our site, be sure to turn on Javascript in your browser. When diluted properly, Cedarwood is a great essential oil safe for controlling fleas and ticks on cats. For best results, brush your cat's fur 24 hours after application to distribute the treatment and the coat conditioning sesame oil. IGRs such as methoprene are used to disrupt and impede the life cycle of insects in the egg and larvae stage of development. © 2020 The Animal Pharmacy. The study was conducted in order to evaluate the effect of a fipronil/(S)-methoprene formulation against fleas on naturally infested cats. Ask your vet to kindly write a prescription. The second ingredient (S)-methoprene acts as an insect growth regulator and destroys the immature life stages of fleas. We will aim to dispatch this product within 24 hours. Adams for cats contains sesame oil as a coat conditioner. Please. Australia's first and only dedicated animal pharmacy, A convenient way to purchase all your pet’s medicines, The most affordable medications for your pet in all of Australia, Fast turnaround so receive your orders promptly, Registered NSW pharmacy providing APVMA approved veterinary medicines, Customer Service: 8am - 6pm | Mon - Fri 8am - 4pm | Saturday, The Animal Pharmacy Shop 2, The Village 3 Julius Avenue North Ryde NSW 2113 Australia, Only registered users can write reviews. ABN 84 154 431 044. It does not kill fleas but disrupts their life cycle, preventing early stages from developing into adults. The activity of the compound as a juvenile hormone is restricted to the S enantiomer. In a normal life cycle, an insect goes from egg to larva to pupa and eventually to adult. Fast Action and Effective - Fleas killed within 24 hours of application on cats - For tick control on cats, use FRONTLINE SPRAY. The ingredient works very fast killing fleas in cats within six hours while those in dogs die in four hours’ time. Methoprene is an insect growth regulator (IGR). (S)-methoprene is a larvicide used to control fleas in dogs and cats. This information is provided for general reference only and is not intended to replace the packaging label or veterinary advice. The product works rapidly and is for use on cats and kittens 12 weeks of age and older. Thus, as you can see, both the Frontline products have the exact same Fipronil content, but the difference lies in the percentage of the ingredient S-Methoprene. For external application. moth). However, as noted in our Buyer’s Guide, pyrethrins are “extremely toxic to cats.” Pyrethrins are also toxic to humans, and therefore please follow the label instructions carefully. Fipronil, methoprene, and cyphenothrin is a combination flea and tick control product that kills existing fleas and ticks and helps prevent new infestations for a full month following application. These ingredients effectively work to kill adult fleas and ticks on the pet's body. It is also used for the treatment and control of chewing lice in dogs, puppies, kittens and cats. The first ingredient – Fipronil acts as adulticide and removes adult fleas and ticks. Please choose wisely as we cannot refund prescription medicines. Skip to the beginning of the images gallery. (S)-Methoprene is an insect growth regulator, or more precisely, a juvenile hormone mimic. Harvey R G et al (1997) Prospective study comparing fipronil with dichlorvos/fenitrothion and methoprene/pyrethrins in control of flea bite hypersensitivity in cats. NSW Pharmacy Registration Number: PC0030058. Frontline contains the active ingredients fipronil and s-methoprene. Vet Parasitol 141(24) 628-629. Safe to use on lactating and pregnant cats. JavaScript seems to be disabled in your browser. The manufacturer says this is an “EPA-regulated spray” that may be applied directly to your cats, cat bedding, carpets, and floor gaps. Phone Australia 131 126.Disposal Wrap empty container in paper and place in garbage. The study involved a population of 89 cats distributed among 24 … cyphenothrin, phenothrin, permethrin, etc.). (S)-methoprene is a larvicide used to control fleas in dogsand cats. Wash hands after use.First Aid If poisoning occurs, contact a doctor or Poisons Information Centre. Extinguish with alcohol-resistant foam, carbon dioxide, dry powder or water fog. Acute Toxicity and Tolerance of Etofenprox. The study was conducted in order to evaluate the effect of a fipronil/(S)-methoprene formulation against fleas on naturally infested cats. Do not use Generic Frontline Plus if you or your pet has a known hypersensitivity to insecticides or alcohol. While remaining in their juvenile form, the insects are unable to reproduce, breaking their life cycle. Mail the original copy of the prescription (no stamp required) to us: The Animal PharmacyReply Paid 88675North Ryde NSW 2113. While Frontline Plus for dogs has 9.8% of Fipronil content and 8.8% of S-methoprene content, Frontline Plus for cats has 9.8% of Fipronil, but 11.8% of S-Methoprene. Rather than killing insects, it controls them by interfering with normal hormone levels within the insect at critical development periods preventing growth and/or maturation. 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